South Africa After Paris—Fracking Its Way to the NDCs?

South Africa faces the triple challenge of (a) fueling its economic development by meeting the rapidly growing energy demand; (b) increasing the reliability of its power system; and (c) letting domestic greenhouse gas emissions peak between 2020 and 2025 in line with its pledge to the UNFCCC under the Paris agreement. Recently discovered domestic shale gas reserves are currently under evaluation as a potential new energy source, to provide clean, reliable and cheap electricity while mitigating greenhouse gas emissions. But, the impact of shale gas on greenhouse gas emissions is far from settled. In order to evaluate if shale gas can play a viable role in solving South Africa’s energy dilemma, we apply a country-level version of the integrated assessment model MESSAGE to analyze and quantify the interdependence between shale gas extraction and climate change mitigation e_ort regarding the South African energy pathways and its domestic greenhouse gas emissions. Our results illustrate, that low cost shale gas can lower the overall energy system costs compared to the no-shale-gas counterfactual. At the same time, a system with abundant low cost natural gas from shale sources requires a stronger carbon price signal compared to the no-shale-gas scenarios in order to achieve the same desired mitigation goals. Therefore, reaching the mitigation goals might be more economically achievable utilizing low cost shale gas in combination with a more stringent climate policy measure compared to a no-shale-gas scenario

The MESSAGEix Integrated Assessment Model and the ix modeling platform (ixmp)

The MESSAGE Integrated Assessment Model (IAM) developed by IIASA has been a central tool of energy-environment-economy systems analysis in the global scientific and policy arena. It played a major role in the Assessment Reports of the Intergovernmental Panel on Climate Change (IPCC); it provided marker scenarios of the Representative Concentration Pathways (RCPs) and the Shared Socio-Economic Pathways (SSPs); and it underpinned the analysis of the Global Energy Assessment (GEA). Alas, to provide relevant analysis for current and future challenges, numerical models of human and earth systems need to support higher spatial and temporal resolution, facilitate integration of data sources and methodologies across disciplines, and become open and transparent regarding the underlying data, methods, and the scientific workflow. In this manuscript, we present the building blocks of a new framework for an integrated assessment modeling platform; the \ecosystem" comprises: i) an open-source GAMS implementation of the MESSAGE energy++ system model integrated with the MACRO economic model; ii) a Java/database backend for version-controlled data management, iii) interfaces for the scientific programming languages Python & R for efficient input data and results processing workflows; and iv) a web-browser-based user interface for model/scenario management and intuitive \drag-and-drop" visualization of results. The framework aims to facilitate the highest level of openness for scientific analysis, bridging the need for transparency with efficient data processing and powerful numerical solvers. The platform is geared towards easy integration of data sources and models across disciplines, spatial scales and temporal disaggregation levels. All tools apply best-practice in collaborative software development, and comprehensive documentation of all building blocks and scripts is generated directly from the GAMS equations and the Java/Python/R source code

The effect of seasoning with herbs on the nutritional, safety and sensory properties of reduced-sodium fermented Cobrançosa cv. table olives

This study aimed at evaluating the effectiveness of seasoning Cobrancosa table olives in a brine with aromatic ingredients, in order to mask the bitter taste given by KCl when added to reduced-sodium fermentation brines. Olives were fermented in two different salt combinations: Brine A, containing 8% NaCl and, Brine B, a reduced-sodium brine, containing 4% NaCl + 4% KCl. After the fermentation the olives were immersed in seasoning brines with NaCl (2%) and the aromatic herbs (thyme, oregano and calamintha), garlic and lemon. At the end of the fermentation and two weeks after seasoning, the physicochemical, nutritional, organoleptic, and microbiological parameters, were determined. The olives fermented in the reduced-sodium brines had half the sodium concentration, higher potassium and calcium content, a lower caloric level, but were considered, by a sensorial panel, more bitter than olives fermented in NaCl brine. Seasoned table olives, previously fermented in Brine A and Brine B, had no significant differences in the amounts of protein (1.23% or 1.11%), carbohydrates (1.0% or 0.66%), fat (20.0% or 20.5%) and dietary fiber (3.4% or 3.6%). Regarding mineral contents, the sodium-reduced fermented olives, presented one third of sodium, seven times more potassium and three times more calcium than the traditional olives fermented in 8% NaCl. Additionally, according to the panelists' evaluation, seasoning the olives fermented in 4% NaCl + 4% KCl, resulted in a decrease in bitterness and an improvement in the overall evaluation and flavor. Escherichia coli and Salmonella were not found in the olives produced.info:eu-repo/semantics/publishedVersio

Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity.

This is the final version of the article. It first appeared from Cell Press via http://dx.doi.org/10.1016/j.cell.2015.12.025More than one-half billion people are obese, and despite progress in genetic research, much of the heritability of obesity remains enigmatic. Here, we identify a Trim28-dependent network capable of triggering obesity in a non-Mendelian, "on/off" manner. Trim28(+/D9) mutant mice exhibit a bi-modal body-weight distribution, with isogenic animals randomly emerging as either normal or obese and few intermediates. We find that the obese-"on" state is characterized by reduced expression of an imprinted gene network including Nnat, Peg3, Cdkn1c, and Plagl1 and that independent targeting of these alleles recapitulates the stochastic bi-stable disease phenotype. Adipose tissue transcriptome analyses in children indicate that humans too cluster into distinct sub-populations, stratifying according to Trim28 expression, transcriptome organization, and obesity-associated imprinted gene dysregulation. These data provide evidence of discrete polyphenism in mouse and man and thus carry important implications for complex trait genetics, evolution, and medicine.This work was supported by funding from the Max-Planck Society, ERC (ERC-StG-281641), DFG (SFB992 “MedEp”; SFB 1052 “ObesityMechanisms”), EU_FP7 (NoE ”Epigenesys”; “Beta-JUDO” n° 279153), BMBF (DEEP), MRC (Metabolic Disease Unit - APC, SOR, GSHY, MRC_MC_UU_12012/1), Wellcome Trust (SOR, 095515/Z/11/Z) and the German Research Council (DFG) for the Clinical Research Center "Obesity Mechanisms" CRC1052/1 C05 and the Federal Ministry of Education and Research, Germany, FKZ, 01EO1001 (Integrated Research and Treatment Center (IFB) Adiposity Diseases

Decolonisation of institutional structures in South African universities: A critical perspective

In 2015, using social media, a new generation of South African university students launched the social justice movement #FeesMustFall. The call for social justice, equity and equality has been a burning issue in South Africa’s education system since the dark days of apartheid. In 1976, non-white students revolted against the apartheid government and many lost their lives during the protest. On 15 October 2015, 40 years later, students from all demographics mobilised to launch a protest under the theme #FeesMustFall against institutional racism which did not die with apartheid. The roots of this movement are symptomatic of deep social and economic concerns rooted in the apartheid history of South Africa. Through the use of social media, students mobilised protest marches in all regions of the country to demand justice, equality and equity. This paper discusses and describes the lack of transformation in South Africa’s higher education which has perpetuated institutional racism for decades

Piketty comes to South Africa

One of the most valuable features of Capital and Ideology is its concern to take history seriously and consider how the eme

Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes

Type-2 diabetes results from the development of insulin resistance and a concomitant impairment of insulin secretion. Recent studies place altered mitochondrial oxidative phosphorylation (OxPhos) as an underlying genetic element of insulin resistance. However, the causative or compensatory nature of these OxPhos changes has yet to be proven. Here, we show that muscle-and liver-specific AIF ablation in mice initiates a pattern of OxPhos deficiency closely mimicking that of human insulin resistance, and contrary to current expectations, results in increased glucose tolerance, reduced fat mass, and increased insulin sensitivity. These results are maintained upon high-fat feeding and in both genetic mosaic and ubiquitous OxPhos-deficient mutants. Importantly, the effects of AIF on glucose metabolism are acutely inducible and reversible. These findings establish that tissue-specific as well as global OxPhos defects in mice can counteract the development of insulin resistance, diabetes, and obesity